Endemic goitre and thyroid function in Central Africa.

نویسنده

  • F Delange
چکیده

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The aetiology, prevention and treatment of simple goitre.

Introduction Simple goitre has afflicted mankind since the earliest times. It was known to the Chinese about 1500 B.C., to the ancient Greeks and to the Romans. Humbolt, in I824, observed it among the natives of the Andes and Livingstone among those of Central Africa. Two thousand years ago sea salt was known to be beneficial and burnt sea sponge was a remedy in use from the times of the ancien...

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Multinodular Thyroid Disease

Multinodular goitre is the most prevalent thyroid pathological abnormality worldwide, although its geographical incidence varies greatly according to environmental iodization Most countries in central and southern Europe have endemic goitre areas with a prevalence of multinodular goitre (MG) of 3-6%. In United States, the annual incidence of nodular thyroid disease is 0.1% to 1.5% and the preva...

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Endemic goitre and hypothyroidism in an adult female patient dependent on total parenteral nutrition

We present the case of a thirty-year-old female patient who was referred to the endocrinology team with an enlarging goitre and biochemical hypothyroidism. She had been dependent on total parenteral nutrition for the previous six years as a result of intestinal failure thought to be caused by possible underlying mitochondrial disease. The patient also suffers from a Desmin myopathy, and at pres...

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A Case of Sporadic Congenital Goitre

Since the general use of iodine prophylactically in endemic goitre areas gross enlargement of the thyroid gland at birth has become relatively uncommon. Wegelin's (1926) series in the preiodine period of 223 consecutive necropsies on newborn infants in a goitre area between 1911 and 1921 showed that 340% had thyroid glands weighing over 6 g. The normal weight of the gland at birth in a healthy ...

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Radioiodine - an attractive alternative to surgery in large non-toxic multinodular goitres.

Sporadic non-toxic goitre (SNG) is defined as thyroid enlargement in a euthyroid patient living in an area without endemic goitre. Because thyroid hormone function is within the reference range, the main problems are the signs of thyroid enlargement, thus reducing the size of the goitre is undoubtedly the primary goal of therapy. Although SNG is a common disease, there is no single optimal mana...

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عنوان ژورنال:
  • Monographs in paediatrics

دوره 2 0  شماره 

صفحات  -

تاریخ انتشار 1974